Thursday, April 3, 1997
9:00 Welcoming Remarks - Dr. Fred Roberts, Director DIMACS 9:15 Introduction and General Overview Wilma Olson, Rutgers University Craig Benham, Mount Sinai School of Medicine (session chair) Biology and Physics of DNA Deformation 9:25 Andrzej Stasiak, Universite de Lausanne Biological Function of RecA-induced DNA Stretching and Unwinding 10:05 Steven M. Block, Princeton University Stretching DNA with Optical Tweezers 10:45 - 11:15 Coffee Break 11:15 Phil Nelson, University of Pennsylvania Direct Determination of DNA Twist-Stretch Coupling 11:55 Suse Broyde,New York University Computed Structures of DNA Damaged by Activated Benzo[a]pyrenes 12:30 Discussion 12:40 - 2:00 Lunch Break Tamar Schlick, Howard Hughes Medical Institute and New York University (session chair) Recent Developments of Elastic Rod Models of DNA 2:00 Alexander V. Vologodskii, New York University Catenation Probability in Supercoiled DNA 2:40 Irwin Tobias, Rutgers University Thermal Fluctuations in DNA Minicircles 3:20 Isaac Klapper, Montana State University Dynamics of Elastic Rods, Knots, Curves 4:00 - 4:30 Coffee Break 4:30 Bernard D. Coleman, Rutgers University Theory of the Influence of End Conditions on the Tertiary Structure of DNA 5:10 Marcia O. Fenley, Continuum Dynamics, Inc. Supercoiled DNA Polyelectrolyte 5:50 Discussion 6:30 - 9:00 Dinner Reception and Poster Session
Friday, April 4, 1997 Bill Bauer, State University of New York Stony Brook (session chair) DNA Sequence, Structure, and Activity 9:00 Craig J. Benham, Mount Sinai School of Medicine Superhelical Duplex Destabilization and DNA Regulation 9:40 Victor B. Zhurkin, National Institutes of Health DNA Bending and Writhing in Complexes with Proteins: Analyzing Crystal Structures and Modeling the p53-DNA Complex 10:20 Gadi Fibich, University of California, Los Angeles A Mathematical Model of Transcription Regulation of a Single Gene 11:00 - 11:20 Coffee Break Alex Vologodskii, New York University (session chair) Topological Forms 11:20 Valentin Rybenkov and Nicholas R. Cozzarelli University of California, Berkeley Topological Equilibrium in Circular DNA 12:00 Jonathan Simon, University of Iowa Energy, Thickness, and Compaction of Knots 12:50 Discussion 12:50 - 1:40 Lunch Break Wilma Olson, Rutgers University (session chair) Nucleosomal DNA 1:40 Ariel Prunell, Centre National de la Recherche Scientifique et Universite Paris Conformational Flexibility of the Histone (H3-H4)2 Tetramer of the Nucleosome Viewed Through DNA Topology 2:20 David Clark, National Institutes of Health The Nucleosome: A Barrier to Transcription 3:00 Jordanka Zlatanova, Oregon State University Chromatin Higher-order Structure 3:40 Discussion and Refreshments